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ProlongMD vs Renew Youth: Which Is Better?

Head-to-head comparison of ProlongMD and Renew Youth based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Renew Youth scores higher overall in our independent evaluation (61.2/100 vs 60.1/100), leading on trust & safety, experience, product range, reputation. ProlongMD comes out ahead on value.

60

Small, veteran-owned cash-pay telehealth practice offering compounded GLP-1s, TRT, enclomiphene, women's hormones, ED, hair loss and peptides after a $79 video consult.

Visit ProlongMD
61

Renew Youth is a long-running (since 1999) bioidentical hormone and longevity practice serving men and women through a national network of affiliated physicians, with pricing disclosed only after a phone consultation.

Visit Renew Youth

Score Breakdown

DimensionProlongMDRenew Youth
Overall Score60.1/10061.2/100 ✓
Trust & Safety30%52/10055/100 ✓
Value25%74/100 ✓50/100
Experience20%55/10066/100 ✓
Product Range15%70/10080/100 ✓
Reputation10%45/10070/100 ✓

At a Glance

Founded20251999
HeadquartersPhoenix, AZWisconsin
Publicly tradedNoNo
Treatment categories87
Treatments listed135
Starting price$25/mo—

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryProlongMDRenew Youth
Weight Loss / GLP-1$99–$119
Compounded Semaglutide/B12
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Hormone Therapy$89–$119
Testosterone Cypionate (200 mg/mL)
—
Men's Health$129–$159
Enclomiphene 25 mg
—
Women's Health$33
Progesterone (oral)
—
Sexual Health$75
Tadalafil 24 mg
—
Hair Loss$25
Oral Finasteride 5 mg
—
Longevity & Peptides$179
Sermorelin
—

ProlongMD

+Low published prices: compounded semaglutide/B12 from $99/mo and tirzepatide/B12 from $149/mo, with no membership fee
+$79 video consult is credited toward the first treatment purchase, and a written price-match policy covers comparable injectable programs
+Names its prescribing clinicians (two physicians, two nurse practitioners) and runs synchronous video visits
−Sells BPC-157/TB-500 and GHK-Cu/BPC-157/KPV/TB-500 'peptide blends', compounds the FDA has flagged for safety concerns and which have no approved drug form
−Dispensing pharmacies are not named, and the states served are not published (visible reviews come only from TX and CO)
−Very new (LLC formed August 2025) with no independent review footprint; several on-site star ratings have no review text
Read the full ProlongMD review →

Renew Youth

+About 27 years in hormone therapy, one of the longest operating histories among brands reviewed
+Full-spectrum hormone care for both sexes, including thyroid, DHEA/pregnenolone, and adrenal support alongside testosterone and estrogen/progesterone
+4.6/5 Trustpilot rating across about 260 reviews, with the company replying to every negative review
−No pricing published anywhere on the site; costs are disclosed only after a phone consultation
−Treatment pages make overstated safety claims (e.g., testosterone "does not cause prostate cancer," therapy should have "no side effects")
−Reviewers report week-long prescription processing on top of shipping time
Read the full Renew Youth review →

ProlongMD vs Renew Youth — FAQ

Is ProlongMD better than Renew Youth?

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Renew Youth scores higher overall in our independent evaluation (61.2/100 vs 60.1/100), leading on trust & safety, experience, product range, reputation. ProlongMD comes out ahead on value.

What do ProlongMD and Renew Youth both offer?

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Both platforms treat Weight Loss / GLP-1, Hormone Therapy, Men's Health, Women's Health, Sexual Health, Hair Loss, Longevity & Peptides. ProlongMD covers 8 treatment categories total and Renew Youth covers 7.

Still deciding?

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