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Renew Youth vs RxSpan MD: Which Is Better?

Head-to-head comparison of Renew Youth and RxSpan MD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Renew Youth scores higher overall in our independent evaluation (61.2/100 vs 59.1/100), leading on experience, product range, reputation. RxSpan MD comes out ahead on trust & safety, value.

Renew Youth is a long-running (since 1999) bioidentical hormone and longevity practice serving men and women through a national network of affiliated physicians, with pricing disclosed only after a phone consultation.

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RxSpan MD is a Beverly Hills telehealth practice founded by a plastic surgeon, offering compounded and branded GLP-1s, longevity peptides, hair-loss and ED treatment.

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Score Breakdown

DimensionRenew YouthRxSpan MD
Overall Score61.2/100 ✓59.1/100
Trust & Safety30%55/10060/100 ✓
Value25%50/10058/100 ✓
Experience20%66/100 ✓52/100
Product Range15%80/100 ✓78/100
Reputation10%70/100 ✓45/100

At a Glance

Founded19992026
HeadquartersWisconsinBeverly Hills, CA
Publicly tradedNoNo
Treatment categories74
Treatments listed59
Starting price—$30/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryRenew YouthRxSpan MD
Weight Loss / GLP-1—$249–$299
Compounded Semaglutide (injection or oral)
Sexual Health—$30–$100
ED (tadalafil, sildenafil/pycnogenol, vardenafil)
Hair Loss—$30–$80
Hair Loss (oral minoxidil, finasteride/minoxidil, dutasteride)
Longevity & Peptides—$100–$200
Glutathione

Renew Youth

+About 27 years in hormone therapy, one of the longest operating histories among brands reviewed
+Full-spectrum hormone care for both sexes, including thyroid, DHEA/pregnenolone, and adrenal support alongside testosterone and estrogen/progesterone
+4.6/5 Trustpilot rating across about 260 reviews, with the company replying to every negative review
−No pricing published anywhere on the site; costs are disclosed only after a phone consultation
−Treatment pages make overstated safety claims (e.g., testosterone "does not cause prostate cancer," therapy should have "no side effects")
−Reviewers report week-long prescription processing on top of shipping time
Read the full Renew Youth review →

RxSpan MD

+Physician-founded practice with a named founder and a stated Beverly Hills address
+Offers both compounded (injection and oral) and branded GLP-1s, including cash-pay Zepbound listed at $500
+Third-party coverage reports named 503A pharmacy partners and free expedited shipping
−Compounded prices aren't visible on the public site; its product catalog failed to load during our research
−Brand-stated first-month prices ($249 semaglutide, $329 tirzepatide) are above peer averages, and renewal pricing is not published
−Site configuration shows an $80 initial visit fee that is not prominently disclosed
Read the full RxSpan MD review →

Renew Youth vs RxSpan MD — FAQ

Is Renew Youth better than RxSpan MD?

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Renew Youth scores higher overall in our independent evaluation (61.2/100 vs 59.1/100), leading on experience, product range, reputation. RxSpan MD comes out ahead on trust & safety, value.

What do Renew Youth and RxSpan MD both offer?

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Both platforms treat Weight Loss / GLP-1, Sexual Health, Hair Loss, Longevity & Peptides. Renew Youth covers 7 treatment categories total and RxSpan MD covers 4.

Still deciding?