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Renew Youth vs System Labs: Which Is Better?

Head-to-head comparison of Renew Youth and System Labs based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Renew Youth scores higher overall in our independent evaluation (61.2/100 vs 56.4/100), leading on trust & safety, experience, product range, reputation. System Labs comes out ahead on value.

61

Renew Youth is a long-running (since 1999) bioidentical hormone and longevity practice serving men and women through a national network of affiliated physicians, with pricing disclosed only after a phone consultation.

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56

System Labs is a San Francisco-based telehealth service prescribing compounded NAD+, sermorelin, glutathione and MIC-B12, with half-price first months.

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Score Breakdown

DimensionRenew YouthSystem Labs
Overall Score61.2/100 ✓56.4/100
Trust & Safety30%55/100 ✓52/100
Value25%50/10068/100 ✓
Experience20%66/100 ✓55/100
Product Range15%80/100 ✓55/100
Reputation10%70/100 ✓45/100

At a Glance

Founded1999—
HeadquartersWisconsinSan Francisco, CA
Publicly tradedNoNo
Treatment categories71
Treatments listed56
Starting price—$89/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryRenew YouthSystem Labs
Longevity & Peptides—$89
MIC+B12 Injection

Renew Youth

+About 27 years in hormone therapy, one of the longest operating histories among brands reviewed
+Full-spectrum hormone care for both sexes, including thyroid, DHEA/pregnenolone, and adrenal support alongside testosterone and estrogen/progesterone
+4.6/5 Trustpilot rating across about 260 reviews, with the company replying to every negative review
−No pricing published anywhere on the site; costs are disclosed only after a phone consultation
−Treatment pages make overstated safety claims (e.g., testosterone "does not cause prostate cancer," therapy should have "no side effects")
−Reviewers report week-long prescription processing on top of shipping time
Read the full Renew Youth review →

System Labs

+Every price is posted on the site, including a first-month discount of roughly 40–50%
+Names its main compounding pharmacy (The Pharmacy Hub, Miami) and three board-certified physician advisors
+Both injectable and non-injectable options (NAD+ nasal spray, oral sermorelin)
−Trustpilot removed its business profile for guideline violations, so there is no independent review base
−'20k+ patients' claim is unverified; founding date and company history are not disclosed
−All sales are final once shipped; terms impose binding arbitration and a class-action waiver
Read the full System Labs review →

Renew Youth vs System Labs — FAQ

Is Renew Youth better than System Labs?

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Renew Youth scores higher overall in our independent evaluation (61.2/100 vs 56.4/100), leading on trust & safety, experience, product range, reputation. System Labs comes out ahead on value.

What do Renew Youth and System Labs both offer?

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Both platforms treat Longevity & Peptides. Renew Youth covers 7 treatment categories total and System Labs covers 1.

Still deciding?

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