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Renew Youth vs Twentyeight Health: Which Is Better?

Head-to-head comparison of Renew Youth and Twentyeight Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 61.2/100), leading on trust & safety, value, experience. Renew Youth comes out ahead on product range.

61

Renew Youth is a long-running (since 1999) bioidentical hormone and longevity practice serving men and women through a national network of affiliated physicians, with pricing disclosed only after a phone consultation.

Visit Renew Youth
75

Brooklyn-based women's telehealth service covering birth control, emergency contraception, UTI/BV/yeast and herpes treatment, prescription skincare and branded GLP-1s under a $19.99/mo membership ($0 in-network).

Visit Twentyeight Health

Score Breakdown

DimensionRenew YouthTwentyeight Health
Overall Score61.2/10075/100 ✓
Trust & Safety30%55/10076/100 ✓
Value25%50/10080/100 ✓
Experience20%66/10072/100 ✓
Product Range15%80/100 ✓72/100
Reputation10%70/10070/100

At a Glance

Founded19992018
HeadquartersWisconsinBrooklyn, NY
Publicly tradedNoNo
Treatment categories74
Treatments listed57
Starting price—$15/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryRenew YouthTwentyeight Health
Women's Health—$15–$19.99
Complete Care Membership
Weight Loss / GLP-1——
Sexual Health——

Renew Youth

+About 27 years in hormone therapy, one of the longest operating histories among brands reviewed
+Full-spectrum hormone care for both sexes, including thyroid, DHEA/pregnenolone, and adrenal support alongside testosterone and estrogen/progesterone
+4.6/5 Trustpilot rating across about 260 reviews, with the company replying to every negative review
−No pricing published anywhere on the site; costs are disclosed only after a phone consultation
−Treatment pages make overstated safety claims (e.g., testosterone "does not cause prostate cancer," therapy should have "no side effects")
−Reviewers report week-long prescription processing on top of shipping time
Read the full Renew Youth review →

Twentyeight Health

+Low entry cost: $19.99/mo membership ($0 when in-network), birth control from $16/pack cash and often $0 with insurance
+Accepts most commercial insurance and Medicaid in multiple states, which few D2C telehealth brands do
+One membership covers contraception, EC, UTI/BV/yeast, herpes, skincare and weight care, and urgent-care prescriptions are ready for pickup in 4–6 hours
−Medications are billed separately from the membership, which some reviewers say caused unexpected charges
−Weight care (branded Wegovy/Zepbound only) is limited to about 22 states, and skincare to a subset of states
−21% of Trustpilot reviews are 1-star, citing billing discrepancies and support communication problems
Read the full Twentyeight Health review →

Renew Youth vs Twentyeight Health — FAQ

Is Renew Youth better than Twentyeight Health?

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Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 61.2/100), leading on trust & safety, value, experience. Renew Youth comes out ahead on product range.

What do Renew Youth and Twentyeight Health both offer?

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Both platforms treat Women's Health, Weight Loss / GLP-1, Sexual Health. Renew Youth covers 7 treatment categories total and Twentyeight Health covers 4.

Still deciding?

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