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Sprout Health vs Synergy Rx: Which Is Better?

Head-to-head comparison of Sprout Health and Synergy Rx based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Synergy Rx scores higher overall in our independent evaluation (51.9/100 vs 50.9/100), leading on trust & safety, experience, product range. Sprout Health comes out ahead on value, reputation.

51
Sprout Health
Below Average

Sprout Health is an Encinitas, CA telehealth brand selling compounded semaglutide, tirzepatide and NAD+. It received an FDA warning letter in September 2025 and has an F rating from the BBB.

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52
Synergy Rx
Below Average

Synergy Rx is a GLP-1 and peptide storefront launched in 2026 on CareValidate's white-label platform. It sells compounded semaglutide and tirzepatide as injections or oral tablets, prescribed through the Lion MD network.

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Score Breakdown

DimensionSprout HealthSynergy Rx
Overall Score50.9/10051.9/100 ✓
Trust & Safety30%45/10048/100 ✓
Value25%62/100 ✓60/100
Experience20%48/10050/100 ✓
Product Range15%55/10058/100 ✓
Reputation10%40/100 ✓38/100

At a Glance

Founded20212026
HeadquartersEncinitas, CA—
Publicly tradedNoNo
Treatment categories23
Treatments listed59
Starting price$149/mo$109/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategorySprout HealthSynergy Rx
Weight Loss / GLP-1$149–$249
Compounded Semaglutide
$199
Compounded Semaglutide (injectable)
Longevity & Peptides$199–$240
Compounded NAD+ Injections
$109
B12 Methylcobalamin

Sprout Health

+Offers both compounded (semaglutide, tirzepatide) and branded (Wegovy, Zepbound) GLP-1s alongside NAD+
+Entry pricing ($149/mo semaglutide, $199/mo tirzepatide) is published before intake
+Prescribing runs through MD Integrations, an established white-label physician network
−FDA warning letter (Sept 9, 2025) for marketing compounded GLP-1s as 'FDA-approved'
−BBB rating of F for failing to respond to complaints; multiple reports of patients forced to use chargebacks or stop-payments to cancel
−Recurring complaints of late or missing refills, wrong doses shipped, and no phone support
Read the full Sprout Health review →

Synergy Rx

+Offers both injectable and oral-tablet compounded semaglutide and tirzepatide
+Names its four dispensing pharmacies and supervising Lion MD physicians
+Wider peptide menu than sibling storefronts: NAD+, sermorelin, glutathione, B12, PT-141
−Independent review found the intake does not screen for medullary thyroid cancer or MEN2 history (GLP-1 boxed-warning contraindication)
−Pricing is withheld until after the consult on the brand's own site; consult fee is disclosed inconsistently ($59 vs $80)
−Launched in 2026 with no Trustpilot, BBB or patient-review history
Read the full Synergy Rx review →

Sprout Health vs Synergy Rx — FAQ

Is Sprout Health better than Synergy Rx?

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Synergy Rx scores higher overall in our independent evaluation (51.9/100 vs 50.9/100), leading on trust & safety, experience, product range. Sprout Health comes out ahead on value, reputation.

Is Sprout Health or Synergy Rx cheaper?

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Synergy Rx has the lower starting price (from $109/mo vs $149/mo for Sprout Health). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Sprout Health and Synergy Rx both offer?

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Both platforms treat Weight Loss / GLP-1, Longevity & Peptides. Sprout Health covers 2 treatment categories total and Synergy Rx covers 3.

Still deciding?

Sprout Health alternativesSynergy Rx alternativesTake the Match Quiz