Home›Compare›Synergy Rx vs Wellmedr

Synergy Rx vs Wellmedr: Which Is Better?

Head-to-head comparison of Synergy Rx and Wellmedr based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Wellmedr scores higher overall in our independent evaluation (60.8/100 vs 51.9/100), leading on trust & safety, value, experience, product range, reputation.

52
Synergy Rx
Below Average

Synergy Rx is a GLP-1 and peptide storefront launched in 2026 on CareValidate's white-label platform. It sells compounded semaglutide and tirzepatide as injections or oral tablets, prescribed through the Lion MD network.

Visit Synergy Rx
61

Wellmedr is a St. Petersburg, FL telehealth brand launched in 2025. It sells low-priced compounded semaglutide and tirzepatide plus ED, enclomiphene, hair-loss and NAD+ treatments, prescribed through OpenLoop Health.

Visit Wellmedr

Score Breakdown

DimensionSynergy RxWellmedr
Overall Score51.9/10060.8/100 ✓
Trust & Safety30%48/10050/100 ✓
Value25%60/10078/100 ✓
Experience20%50/10055/100 ✓
Product Range15%58/10072/100 ✓
Reputation10%38/10045/100 ✓

At a Glance

Founded20262025
Headquarters—St. Petersburg, FL
Publicly tradedNoNo
Treatment categories36
Treatments listed96
Starting price$109/mo$40/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategorySynergy RxWellmedr
Weight Loss / GLP-1$199
Compounded Semaglutide (injectable)
$49–$149
Compounded Semaglutide (+NAD+/B12)
Longevity & Peptides$109
B12 Methylcobalamin
$120–$200
NAD+
Sexual Health$275
PT-141 (bremelanotide)
$60–$120
Black Pill 3-in-1 (sildenafil/tadalafil/apomorphine)

Synergy Rx

+Offers both injectable and oral-tablet compounded semaglutide and tirzepatide
+Names its four dispensing pharmacies and supervising Lion MD physicians
+Wider peptide menu than sibling storefronts: NAD+, sermorelin, glutathione, B12, PT-141
−Independent review found the intake does not screen for medullary thyroid cancer or MEN2 history (GLP-1 boxed-warning contraindication)
−Pricing is withheld until after the consult on the brand's own site; consult fee is disclosed inconsistently ($59 vs $80)
−Launched in 2026 with no Trustpilot, BBB or patient-review history
Read the full Synergy Rx review →

Wellmedr

+Some of the lowest compounded GLP-1 prices we track: $49/mo semaglutide and $89/mo tirzepatide on 12-month plans, the same at every dose
+Broad catalog for a new brand, spanning GLP-1s, a 3-in-1 ED pill, enclomiphene, a 4-in-1 hair-loss formula and NAD+
+Unlimited clinician messaging and 1–4 hour approval target; 90-day money-back guarantee advertised
−BBB rating of F with 75 complaints since its May 2025 start; BBB flagged a pattern of late or temperature-mishandled deliveries, charges after cancellation and refused guarantee refunds
−Reviewers report billing every 21 days rather than monthly, which adds charges over a year
−Dispensing pharmacies are not named, and prescribing is outsourced to OpenLoop Health and 'other networks'
Read the full Wellmedr review →

Synergy Rx vs Wellmedr — FAQ

Is Synergy Rx better than Wellmedr?

▾

Wellmedr scores higher overall in our independent evaluation (60.8/100 vs 51.9/100), leading on trust & safety, value, experience, product range, reputation.

Is Synergy Rx or Wellmedr cheaper?

▾

Wellmedr has the lower starting price (from $40/mo vs $109/mo for Synergy Rx). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Synergy Rx and Wellmedr both offer?

▾

Both platforms treat Weight Loss / GLP-1, Longevity & Peptides, Sexual Health. Synergy Rx covers 3 treatment categories total and Wellmedr covers 6.

Still deciding?

Synergy Rx alternativesWellmedr alternativesTake the Match Quiz