Home›Compare›Synergy Rx vs Wisp

Synergy Rx vs Wisp: Which Is Better?

Head-to-head comparison of Synergy Rx and Wisp based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Wisp scores higher overall in our independent evaluation (73.6/100 vs 51.9/100), leading on trust & safety, value, experience, product range, reputation.

52
Synergy Rx
Below Average

Synergy Rx is a GLP-1 and peptide storefront launched in 2026 on CareValidate's white-label platform. It sells compounded semaglutide and tirzepatide as injections or oral tablets, prescribed through the Lion MD network.

Visit Synergy Rx
74
Wisp
Good

Async telehealth platform for sexual and reproductive health, prescribing UTI, BV, yeast, herpes, STI, birth control, and menopause treatment at scale with no consult fee.

Visit Wisp

Score Breakdown

DimensionSynergy RxWisp
Overall Score51.9/10073.6/100 ✓
Trust & Safety30%48/10072/100 ✓
Value25%60/10078/100 ✓
Experience20%50/10070/100 ✓
Product Range15%58/10075/100 ✓
Reputation10%38/10072/100 ✓

At a Glance

Founded20262018
Headquarters—Austin, TX
Publicly tradedNoNo
Treatment categories34
Treatments listed94
Starting price$109/mo$5/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategorySynergy RxWisp
Weight Loss / GLP-1$199
Compounded Semaglutide (injectable)
—
Sexual Health$275
PT-141 (bremelanotide)
$40–$70
Herpes / Cold Sore Antiviral Treatment

Synergy Rx

+Offers both injectable and oral-tablet compounded semaglutide and tirzepatide
+Names its four dispensing pharmacies and supervising Lion MD physicians
+Wider peptide menu than sibling storefronts: NAD+, sermorelin, glutathione, B12, PT-141
−Independent review found the intake does not screen for medullary thyroid cancer or MEN2 history (GLP-1 boxed-warning contraindication)
−Pricing is withheld until after the consult on the brand's own site; consult fee is disclosed inconsistently ($59 vs $80)
−Launched in 2026 with no Trustpilot, BBB or patient-review history
Read the full Synergy Rx review →

Wisp

+No consult fee, with async intake and prescriptions typically issued within hours
+Broad service line under one account: UTI, BV, yeast, herpes, STI treatment/prevention (including DoxyPEP), birth control, and menopause care
+Large scale and review base (2M+ patients, 11,496 Trustpilot reviews at 4.1) indicating consistent service delivery
−Recurring reports of patients being charged for prescriptions that were never sent to the pharmacy, paired with difficulty reaching phone support
−Some patients report side effects or mismatched treatment, suggesting async intake screening can miss individual nuance a live visit would catch
−Weight-care and membership pricing are not fully published prior to starting an intake
Read the full Wisp review →

Synergy Rx vs Wisp — FAQ

Is Synergy Rx better than Wisp?

▾

Wisp scores higher overall in our independent evaluation (73.6/100 vs 51.9/100), leading on trust & safety, value, experience, product range, reputation.

Is Synergy Rx or Wisp cheaper?

▾

Wisp has the lower starting price (from $5/mo vs $109/mo for Synergy Rx). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Synergy Rx and Wisp both offer?

▾

Both platforms treat Weight Loss / GLP-1, Sexual Health. Synergy Rx covers 3 treatment categories total and Wisp covers 4.

Still deciding?

Synergy Rx alternativesWisp alternativesTake the Match Quiz