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Tuyo Health vs Twentyeight Health: Which Is Better?

Head-to-head comparison of Tuyo Health and Twentyeight Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 67.2/100), leading on trust & safety, value, experience, reputation. Tuyo Health comes out ahead on product range. Tuyo Health has the lower entry price (from $4/mo vs $15/mo), so the better value depends on which treatment you need.

Tuyo Health is a Miami-based, physician-founded bilingual (Spanish/English) telehealth service offering GLP-1 weight loss, testosterone, ED, hair loss, birth control, and low-cost primary care to a primarily Latino patient base.

Visit Tuyo Health

Brooklyn-based women's telehealth service covering birth control, emergency contraception, UTI/BV/yeast and herpes treatment, prescription skincare and branded GLP-1s under a $19.99/mo membership ($0 in-network).

Visit Twentyeight Health

Score Breakdown

DimensionTuyo HealthTwentyeight Health
Overall Score67.2/10075/100 ✓
Trust & Safety30%56/10076/100 ✓
Value25%74/10080/100 ✓
Experience20%68/10072/100 ✓
Product Range15%82/100 ✓72/100
Reputation10%60/10070/100 ✓

At a Glance

Founded20242018
HeadquartersMiami, FLBrooklyn, NY
Publicly tradedNoNo
Treatment categories84
Treatments listed137
Starting price$4/mo$15/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryTuyo HealthTwentyeight Health
Weight Loss / GLP-1$99
Metformin (weight program)
—
Sexual Health$4–$7
Generic Sildenafil / Tadalafil
—
Women's Health—$15–$19.99
Complete Care Membership

Tuyo Health

+Fully bilingual (Spanish/English) care team, a meaningful access differentiator for Spanish-speaking patients
+Physician-founded, with a named medical director (Dr. Germán Echeverry, MD)
+Transparent, low published pricing: compounded semaglutide from $155/mo with labs every 3 months and no membership fee; finasteride $18/mo; primary care $9.99/mo
−Received an FDA warning letter (September 2025) for marketing compounded semaglutide and tirzepatide as the "same active" ingredient as Wegovy, Ozempic, Zepbound, and Mounjaro
−Operates in only 20 states
−Reviewers report slow refunds and a $129 initial fee charged to patients later found unsuitable for the program
Read the full Tuyo Health review →

Twentyeight Health

+Low entry cost: $19.99/mo membership ($0 when in-network), birth control from $16/pack cash and often $0 with insurance
+Accepts most commercial insurance and Medicaid in multiple states, which few D2C telehealth brands do
+One membership covers contraception, EC, UTI/BV/yeast, herpes, skincare and weight care, and urgent-care prescriptions are ready for pickup in 4–6 hours
−Medications are billed separately from the membership, which some reviewers say caused unexpected charges
−Weight care (branded Wegovy/Zepbound only) is limited to about 22 states, and skincare to a subset of states
−21% of Trustpilot reviews are 1-star, citing billing discrepancies and support communication problems
Read the full Twentyeight Health review →

Tuyo Health vs Twentyeight Health — FAQ

Is Tuyo Health better than Twentyeight Health?

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Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 67.2/100), leading on trust & safety, value, experience, reputation. Tuyo Health comes out ahead on product range. Tuyo Health has the lower entry price (from $4/mo vs $15/mo), so the better value depends on which treatment you need.

Is Tuyo Health or Twentyeight Health cheaper?

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Tuyo Health has the lower starting price (from $4/mo vs $15/mo for Twentyeight Health). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Tuyo Health and Twentyeight Health both offer?

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Both platforms treat Weight Loss / GLP-1, Sexual Health, Women's Health. Tuyo Health covers 8 treatment categories total and Twentyeight Health covers 4.

Still deciding?