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Twentyeight Health vs Winona: Which Is Better?

Head-to-head comparison of Twentyeight Health and Winona based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 74.5/100), leading on trust & safety, value, product range. Winona comes out ahead on experience, reputation. Winona has the lower entry price (from $9/mo vs $15/mo), so the better value depends on which treatment you need.

Twentyeight Health

Very Good

Brooklyn-based women's telehealth service covering birth control, emergency contraception, UTI/BV/yeast and herpes treatment, prescription skincare and branded GLP-1s under a $19.99/mo membership ($0 in-network).

Visit Twentyeight Health

Winona

Good

Women-focused telehealth delivering personalized bioidentical hormone replacement therapy for menopause, with in-house compounding pharmacies across 33 states.

Visit Winona

Score Breakdown

Dimension	Twentyeight Health	Winona
Overall Score	75/100 ✓	74.5/100
Trust & Safety30%	76/100 ✓	70/100
Value25%	80/100 ✓	75/100
Experience20%	72/100	85/100 ✓
Product Range15%	72/100 ✓	65/100
Reputation10%	70/100	80/100 ✓

At a Glance

Founded	2018	2020
Headquarters	Brooklyn, NY	Austin, TX
Publicly traded	No	No
Treatment categories	4	5
Treatments listed	7	12
Starting price	$15/mo	$9/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

Category	Twentyeight Health	Winona
Women's Health	$15–$19.99 Complete Care Membership	$9 DHEA Capsules
Sexual Health	—	$79 Sildenafil Arousal Cream (per order, not monthly)
Dermatology	—	$50 Estriol Face Cream with Tretinoin

Twentyeight Health

+Low entry cost: $19.99/mo membership ($0 when in-network), birth control from $16/pack cash and often $0 with insurance

+Accepts most commercial insurance and Medicaid in multiple states, which few D2C telehealth brands do

+One membership covers contraception, EC, UTI/BV/yeast, herpes, skincare and weight care, and urgent-care prescriptions are ready for pickup in 4–6 hours

−Medications are billed separately from the membership, which some reviewers say caused unexpected charges

−Weight care (branded Wegovy/Zepbound only) is limited to about 22 states, and skincare to a subset of states

−21% of Trustpilot reviews are 1-star, citing billing discrepancies and support communication problems

Read the full Twentyeight Health review →

Winona

+Vertically integrated: in-house compounding pharmacies, proprietary EHR, employed physicians

+Strong patient satisfaction: 4.6/5 Trustpilot with 6,000+ reviews, 80% report symptom relief in 3 months

+Accessible pricing: $54-$149/mo for core HRT with free consultations and shipping

−Billing runs every 28 days on monthly supplies, which is 13 charges a year rather than 12

−Six of the hormone products and DHEA are advertised as a 'from' price, with dose-level pricing visible only after an intake, so the figures here are floors rather than what most patients pay

−No insurance billing — entirely out-of-pocket (though HSA/FSA accepted)

Read the full Winona review →

Twentyeight Health vs Winona — FAQ

Is Twentyeight Health better than Winona?

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Is Twentyeight Health or Winona cheaper?

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Winona has the lower starting price (from $9/mo vs $15/mo for Twentyeight Health). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Twentyeight Health and Winona both offer?

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Both platforms treat Women's Health, Sexual Health, Dermatology. Twentyeight Health covers 4 treatment categories total and Winona covers 5.

Still deciding?

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