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Estradiol Online

Brand names: Estrace, Vivelle-Dot, Climara

Estradiol is a bioidentical form of estrogen used in hormone replacement therapy (HRT) for menopause symptoms. Available as tablets, patches, transdermal creams, or vaginal inserts. It's the most commonly prescribed estrogen for menopausal symptom relief.

2 providers on TelehealthMatchFrom $54/mo*

How Estradiol Works

Estradiol replaces the estrogen that the ovaries stop producing during menopause. Declining estrogen causes hot flashes, night sweats, vaginal dryness, mood changes, and bone density loss. By restoring estrogen levels, estradiol alleviates these symptoms and helps protect against osteoporosis.

What to Expect

Hot flashes and night sweats typically improve within 2-4 weeks. Vaginal dryness may take 4-12 weeks to fully resolve. Mood and sleep improvements are usually noticed within the first month. Bone density benefits require long-term use.

Estradiol Pricing Comparison

Sorted by lowest starting price.

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

ProviderScoreProductPrice/moIncludes
Winona
75
Estrogen Tablets (Estradiol)$54
20% off for new customers
Consults Shipping Labs
Visit
Estrogen Patch (FDA-approved)$149
Consults Shipping Labs
Ivim Health
58
Women's Hormone Optimization$199
Consults Shipping Labs
Visit

Common Side Effects

  • Breast tenderness
  • Headaches
  • Nausea
  • Bloating
  • Mood changes
  • Breakthrough bleeding (early in treatment)

Serious Side Effects

  • !Blood clots (risk is lower with transdermal forms)
  • !Stroke
  • !Breast cancer (with long-term use, especially combined with progestin)
  • !Endometrial cancer (if taken without progesterone in women with a uterus)

Estradiol Is Not For

  • Women with a history of breast cancer
  • Women with active blood clots or clotting disorders
  • Women with unexplained vaginal bleeding
  • Women with severe liver disease

Estradiol — Frequently Asked Questions

What is estradiol used for?

Estradiol is prescribed to treat menopause symptoms including hot flashes, night sweats, vaginal dryness, and mood changes. It's also used to prevent osteoporosis in postmenopausal women.

How much does estradiol cost from telehealth HRT providers?

Estradiol from telehealth menopause providers typically costs $39-149/month depending on the delivery method. Oral tablets are cheapest, patches are mid-range, and custom compounded creams are most expensive.

Do I need to take progesterone with estradiol?

If you have an intact uterus, yes. Taking estrogen without progesterone increases the risk of endometrial cancer. Women who have had a hysterectomy can typically take estradiol alone. Your provider will determine the right combination.

Medical disclaimer: The information on this page is for educational purposes only and is not medical advice.Estradiol requires a prescription from a licensed healthcare provider. Side effects, risks, and suitability vary by individual. Always consult your doctor before starting, stopping, or changing any medication. TelehealthMatch is not a healthcare provider.

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