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Collective vs Defy Medical: Which Is Better?

Head-to-head comparison of Collective and Defy Medical based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 68.6/100), leading on trust & safety, experience, product range, reputation. Collective comes out ahead on value. Collective has the lower entry price (from $17/mo vs $150/mo), so the better value depends on which treatment you need.

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Collective is a new GLP-1 weight-loss service from Thrive Market founder Gunnar Lovelace. It sells compounded semaglutide at $59/mo and tirzepatide at $69/mo at every dose, plus a $199 annual membership.

Visit Collective
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Physician-led telemedicine hormone clinic offering TRT, women's HRT, peptides, GLP-1s, and sexual-health treatments through its own 503B pharmacy.

Visit Defy Medical

Score Breakdown

DimensionCollectiveDefy Medical
Overall Score68.6/10071.9/100 ✓
Trust & Safety30%66/10072/100 ✓
Value25%90/100 ✓60/100
Experience20%70/10078/100 ✓
Product Range15%45/10078/100 ✓
Reputation10%55/10080/100 ✓

At a Glance

Founded—2011
Headquarters—Tampa, FL
Publicly tradedNoNo
Treatment categories13
Treatments listed34
Starting price$17/mo$150/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryCollectiveDefy Medical
Weight Loss / GLP-1$17
Annual Membership
$150–$250
GLP-1 Weight Loss (Semaglutide/Tirzepatide)

Collective

+Lowest all-in compounded GLP-1 pricing we track: $59/mo semaglutide or $69/mo tirzepatide plus $199/yr membership (about $76–86/mo)
+Flat pricing at every dose, so the monthly cost does not climb during titration
+Membership includes unlimited physician messaging, quarterly dose reviews and registered-dietitian access
−Dispensing pharmacies, medical group and headquarters are not disclosed. The site only says 'state-licensed US pharmacies'
−Very short track record: 38 Trustpilot reviews and no independent press coverage beyond the founder's profile
−GLP-1 weight loss only, with no branded Wegovy/Zepbound option for patients who want FDA-approved product
Read the full Collective review →

Defy Medical

+15 years in operation (founded 2011) — one of the longest-running cash-pay hormone-therapy telehealth brands, with a named Medical Director (Dr. Justin Saya)
+Trustpilot rating of 4.8/5 across 4,144 reviews, and the company responds to 94% of negative reviews, typically within 24 hours
+Broad treatment range from a single provider — TRT, women's HRT, peptides, GLP-1s, sexual dysfunction, and hair loss — dispensed through its own 503B-registered pharmacy with labs required before prescribing
−Pricing is not published on the website; patients must complete a roughly $250 consult before learning treatment costs, a transparency gap versus competitors that post pricing upfront
−Some patients report delays of a week or more between consult and medication fulfillment
−Mobile app quality lags the web experience, per patient feedback
Read the full Defy Medical review →

Collective vs Defy Medical — FAQ

Is Collective better than Defy Medical?

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Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 68.6/100), leading on trust & safety, experience, product range, reputation. Collective comes out ahead on value. Collective has the lower entry price (from $17/mo vs $150/mo), so the better value depends on which treatment you need.

Is Collective or Defy Medical cheaper?

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Collective has the lower starting price (from $17/mo vs $150/mo for Defy Medical). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Collective and Defy Medical both offer?

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Both platforms treat Weight Loss / GLP-1. Collective covers 1 treatment category total and Defy Medical covers 3.

Still deciding?

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