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Collective vs Enhance.MD: Which Is Better?

Head-to-head comparison of Collective and Enhance.MD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Collective scores higher overall in our independent evaluation (68.6/100 vs 66.9/100), leading on value, experience. Enhance.MD comes out ahead on trust & safety, product range, reputation.

Collective is a new GLP-1 weight-loss service from Thrive Market founder Gunnar Lovelace. It sells compounded semaglutide at $59/mo and tirzepatide at $69/mo at every dose, plus a $199 annual membership.

Visit Collective

Enhance.MD is a San Diego-based, physician-directed GLP-1 and NAD+ telehealth program that requires baseline and semiannual labs and video visits before and during treatment.

Visit Enhance.MD

Score Breakdown

DimensionCollectiveEnhance.MD
Overall Score68.6/100 ✓66.9/100
Trust & Safety30%66/10076/100 ✓
Value25%90/100 ✓60/100
Experience20%70/100 ✓68/100
Product Range15%45/10060/100 ✓
Reputation10%55/10065/100 ✓

At a Glance

Founded—2019
Headquarters—San Diego, CA
Publicly tradedNoNo
Treatment categories12
Treatments listed35
Starting price$17/mo$169/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryCollectiveEnhance.MD
Weight Loss / GLP-1$17
Annual Membership
$169
Microdose Tirzepatide

Collective

+Lowest all-in compounded GLP-1 pricing we track: $59/mo semaglutide or $69/mo tirzepatide plus $199/yr membership (about $76–86/mo)
+Flat pricing at every dose, so the monthly cost does not climb during titration
+Membership includes unlimited physician messaging, quarterly dose reviews and registered-dietitian access
−Dispensing pharmacies, medical group and headquarters are not disclosed. The site only says 'state-licensed US pharmacies'
−Very short track record: 38 Trustpilot reviews and no independent press coverage beyond the founder's profile
−GLP-1 weight loss only, with no branded Wegovy/Zepbound option for patients who want FDA-approved product
Read the full Collective review →

Enhance.MD

+Requires baseline labs (CMP, lipids, TSH, HbA1c) before prescribing and repeats them every six months, included in the price
+Named medical director and named fulfilling pharmacies (Tru Meds Rx, Strive, Pharmacy Hub)
+Flat pricing across dose escalation, published before intake, with a full refund if found ineligible
−Billed every 28 days (13 charges a year), making effective annual cost higher than the monthly headline suggests
−Not available in 10 states, including GA, TN and MO
−Trustpilot complaints cite delayed or cancelled shipments and inconsistent results after pharmacy switches
Read the full Enhance.MD review →

Collective vs Enhance.MD — FAQ

Is Collective better than Enhance.MD?

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Collective scores higher overall in our independent evaluation (68.6/100 vs 66.9/100), leading on value, experience. Enhance.MD comes out ahead on trust & safety, product range, reputation.

Is Collective or Enhance.MD cheaper?

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Collective has the lower starting price (from $17/mo vs $169/mo for Enhance.MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Collective and Enhance.MD both offer?

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Both platforms treat Weight Loss / GLP-1. Collective covers 1 treatment category total and Enhance.MD covers 2.

Still deciding?