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Defy Medical vs myLAB Box: Which Is Better?

Head-to-head comparison of Defy Medical and myLAB Box based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 59.7/100), leading on trust & safety, experience, product range, reputation. myLAB Box comes out ahead on value. myLAB Box has the lower entry price (from $99/mo vs $150/mo), so the better value depends on which treatment you need.

Physician-led telemedicine hormone clinic offering TRT, women's HRT, peptides, GLP-1s, and sexual-health treatments through its own 503B pharmacy.

Visit Defy Medical
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At-home lab testing company selling mail-in STD panels and wellness/fertility tests, with a free physician consultation and local-pharmacy prescription for positive results.

Visit myLAB Box

Score Breakdown

DimensionDefy MedicalmyLAB Box
Overall Score71.9/100 ✓59.7/100
Trust & Safety30%72/100 ✓64/100
Value25%60/10062/100 ✓
Experience20%78/100 ✓52/100
Product Range15%78/100 ✓60/100
Reputation10%80/100 ✓56/100

At a Glance

Founded20112014
HeadquartersTampa, FLLos Angeles, CA
Publicly tradedNoNo
Treatment categories33
Treatments listed44
Starting price$150/mo$99/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryDefy MedicalmyLAB Box
Sexual Health—$209
Uber Box (8-Panel STD Test)

Defy Medical

+15 years in operation (founded 2011) — one of the longest-running cash-pay hormone-therapy telehealth brands, with a named Medical Director (Dr. Justin Saya)
+Trustpilot rating of 4.8/5 across 4,144 reviews, and the company responds to 94% of negative reviews, typically within 24 hours
+Broad treatment range from a single provider — TRT, women's HRT, peptides, GLP-1s, sexual dysfunction, and hair loss — dispensed through its own 503B-registered pharmacy with labs required before prescribing
−Pricing is not published on the website; patients must complete a roughly $250 consult before learning treatment costs, a transparency gap versus competitors that post pricing upfront
−Some patients report delays of a week or more between consult and medication fulfillment
−Mobile app quality lags the web experience, per patient feedback
Read the full Defy Medical review →

myLAB Box

+Per-test prices are published openly without an account or intake form
+Positive STD results include a free phone consult with a physician licensed in the customer's state, who can prescribe to a local pharmacy
+Broad catalog (50+ tests) including multi-infection panels up to 14 pathogens (HIV, syphilis, herpes, HPV, Mycoplasma genitalium)
−Recurring Trustpilot complaints about results arriving well after the advertised turnaround, in some cases weeks
−No refunds once samples reach the lab, including when customers cite processing delays
−Comprehensive panels are expensive (14-panel Total Box $379-$409) relative to in-person clinic testing
Read the full myLAB Box review →

Defy Medical vs myLAB Box — FAQ

Is Defy Medical better than myLAB Box?

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Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 59.7/100), leading on trust & safety, experience, product range, reputation. myLAB Box comes out ahead on value. myLAB Box has the lower entry price (from $99/mo vs $150/mo), so the better value depends on which treatment you need.

Is Defy Medical or myLAB Box cheaper?

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myLAB Box has the lower starting price (from $99/mo vs $150/mo for Defy Medical). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Defy Medical and myLAB Box both offer?

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Both platforms treat Sexual Health. Defy Medical covers 3 treatment categories total and myLAB Box covers 3.

Still deciding?