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Defy Medical vs MyMenopauseRx: Which Is Better?

Head-to-head comparison of Defy Medical and MyMenopauseRx based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 61.3/100), leading on value, experience, product range, reputation. MyMenopauseRx comes out ahead on trust & safety.

72

Physician-led telemedicine hormone clinic offering TRT, women's HRT, peptides, GLP-1s, and sexual-health treatments through its own 503B pharmacy.

Visit Defy Medical
61

Gynecologist-founded virtual menopause practice that bills most commercial insurance or charges $150 per self-pay visit, prescribing FDA-approved HRT, non-hormonal therapy and branded GLP-1s to local pharmacies.

Visit MyMenopauseRx

Score Breakdown

DimensionDefy MedicalMyMenopauseRx
Overall Score71.9/100 ✓61.3/100
Trust & Safety30%72/10074/100 ✓
Value25%60/100 ✓58/100
Experience20%78/100 ✓58/100
Product Range15%78/100 ✓50/100
Reputation10%80/100 ✓55/100

At a Glance

Founded20112021
HeadquartersTampa, FLChicago area, IL
Publicly tradedNoNo
Treatment categories33
Treatments listed43
Starting price$150/mo$150/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryDefy MedicalMyMenopauseRx
Hormone Therapy$150–$250
Women's Bioidentical HRT
—
Weight Loss / GLP-1$150–$250
GLP-1 Weight Loss (Semaglutide/Tirzepatide)
—

Defy Medical

+15 years in operation (founded 2011) — one of the longest-running cash-pay hormone-therapy telehealth brands, with a named Medical Director (Dr. Justin Saya)
+Trustpilot rating of 4.8/5 across 4,144 reviews, and the company responds to 94% of negative reviews, typically within 24 hours
+Broad treatment range from a single provider — TRT, women's HRT, peptides, GLP-1s, sexual dysfunction, and hair loss — dispensed through its own 503B-registered pharmacy with labs required before prescribing
−Pricing is not published on the website; patients must complete a roughly $250 consult before learning treatment costs, a transparency gap versus competitors that post pricing upfront
−Some patients report delays of a week or more between consult and medication fulfillment
−Mobile app quality lags the web experience, per patient feedback
Read the full Defy Medical review →

MyMenopauseRx

+Founder and clinicians are named, and most hold Menopause Society certification (MSCP); patients can keep the same clinician
+In-network with major commercial plans, so many insured patients pay only a copay; $150 flat self-pay rate otherwise
+Prescribes FDA-approved therapies to the patient's local pharmacy, and labs can be ordered on demand at discounted self-pay rates
−No cash-pay medication pricing; the cost of HRT or branded GLP-1s depends on the patient's pharmacy and insurance
−Doesn't accept Medicare, Medicaid or HMO plans, and testosterone is offered only in Illinois
−Very thin public reviews (Trustpilot 3.3/5 on 4), including complaints of rushed visits and repeated charges
Read the full MyMenopauseRx review →

Defy Medical vs MyMenopauseRx — FAQ

Is Defy Medical better than MyMenopauseRx?

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Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 61.3/100), leading on value, experience, product range, reputation. MyMenopauseRx comes out ahead on trust & safety.

Is Defy Medical or MyMenopauseRx cheaper?

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Their entry prices are similar — both start around $150/mo. Real cost depends on the specific treatment: compare the pricing tables on each review, since inclusions like consults, labs, and shipping differ.

What do Defy Medical and MyMenopauseRx both offer?

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Both platforms treat Hormone Therapy, Weight Loss / GLP-1. Defy Medical covers 3 treatment categories total and MyMenopauseRx covers 3.

Still deciding?

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