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Defy Medical vs Tuyo Health: Which Is Better?

Head-to-head comparison of Defy Medical and Tuyo Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 67.2/100), leading on trust & safety, experience, reputation. Tuyo Health comes out ahead on value, product range. Tuyo Health has the lower entry price (from $4/mo vs $150/mo), so the better value depends on which treatment you need.

72

Physician-led telemedicine hormone clinic offering TRT, women's HRT, peptides, GLP-1s, and sexual-health treatments through its own 503B pharmacy.

Visit Defy Medical
67

Tuyo Health is a Miami-based, physician-founded bilingual (Spanish/English) telehealth service offering GLP-1 weight loss, testosterone, ED, hair loss, birth control, and low-cost primary care to a primarily Latino patient base.

Visit Tuyo Health

Score Breakdown

DimensionDefy MedicalTuyo Health
Overall Score71.9/100 ✓67.2/100
Trust & Safety30%72/100 ✓56/100
Value25%60/10074/100 ✓
Experience20%78/100 ✓68/100
Product Range15%78/10082/100 ✓
Reputation10%80/100 ✓60/100

At a Glance

Founded20112024
HeadquartersTampa, FLMiami, FL
Publicly tradedNoNo
Treatment categories38
Treatments listed413
Starting price$150/mo$4/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryDefy MedicalTuyo Health
Hormone Therapy$150–$250
Women's Bioidentical HRT
$99–$179
Testosterone Therapy
Weight Loss / GLP-1$150–$250
GLP-1 Weight Loss (Semaglutide/Tirzepatide)
$99
Metformin (weight program)
Sexual Health—$4–$7
Generic Sildenafil / Tadalafil

Defy Medical

+15 years in operation (founded 2011) — one of the longest-running cash-pay hormone-therapy telehealth brands, with a named Medical Director (Dr. Justin Saya)
+Trustpilot rating of 4.8/5 across 4,144 reviews, and the company responds to 94% of negative reviews, typically within 24 hours
+Broad treatment range from a single provider — TRT, women's HRT, peptides, GLP-1s, sexual dysfunction, and hair loss — dispensed through its own 503B-registered pharmacy with labs required before prescribing
−Pricing is not published on the website; patients must complete a roughly $250 consult before learning treatment costs, a transparency gap versus competitors that post pricing upfront
−Some patients report delays of a week or more between consult and medication fulfillment
−Mobile app quality lags the web experience, per patient feedback
Read the full Defy Medical review →

Tuyo Health

+Fully bilingual (Spanish/English) care team, a meaningful access differentiator for Spanish-speaking patients
+Physician-founded, with a named medical director (Dr. Germán Echeverry, MD)
+Transparent, low published pricing: compounded semaglutide from $155/mo with labs every 3 months and no membership fee; finasteride $18/mo; primary care $9.99/mo
−Received an FDA warning letter (September 2025) for marketing compounded semaglutide and tirzepatide as the "same active" ingredient as Wegovy, Ozempic, Zepbound, and Mounjaro
−Operates in only 20 states
−Reviewers report slow refunds and a $129 initial fee charged to patients later found unsuitable for the program
Read the full Tuyo Health review →

Defy Medical vs Tuyo Health — FAQ

Is Defy Medical better than Tuyo Health?

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Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 67.2/100), leading on trust & safety, experience, reputation. Tuyo Health comes out ahead on value, product range. Tuyo Health has the lower entry price (from $4/mo vs $150/mo), so the better value depends on which treatment you need.

Is Defy Medical or Tuyo Health cheaper?

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Tuyo Health has the lower starting price (from $4/mo vs $150/mo for Defy Medical). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Defy Medical and Tuyo Health both offer?

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Both platforms treat Hormone Therapy, Weight Loss / GLP-1, Sexual Health. Defy Medical covers 3 treatment categories total and Tuyo Health covers 8.

Still deciding?

Defy Medical alternativesTuyo Health alternativesTake the Match Quiz