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Niagen Plus vs Renew Youth: Which Is Better?

Head-to-head comparison of Niagen Plus and Renew Youth based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Niagen Plus scores higher overall in our independent evaluation (64.7/100 vs 61.2/100), leading on trust & safety, value. Renew Youth comes out ahead on experience, product range, reputation.

65

Prescription-only telehealth program from Nasdaq-listed Niagen Bioscience (formerly ChromaDex) selling an at-home injection kit of nicotinamide riboside (NR), an NAD+ precursor, rather than NAD+ itself.

Visit Niagen Plus
61

Renew Youth is a long-running (since 1999) bioidentical hormone and longevity practice serving men and women through a national network of affiliated physicians, with pricing disclosed only after a phone consultation.

Visit Renew Youth

Score Breakdown

DimensionNiagen PlusRenew Youth
Overall Score64.7/100 ✓61.2/100
Trust & Safety30%78/100 ✓55/100
Value25%70/100 ✓50/100
Experience20%58/10066/100 ✓
Product Range15%36/10080/100 ✓
Reputation10%68/10070/100 ✓

At a Glance

Founded20241999
HeadquartersLos Angeles, CAWisconsin
Publicly tradedYes (NAGE)No
Treatment categories17
Treatments listed15
Starting price$149/mo—

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryNiagen PlusRenew Youth
Longevity & Peptides$149
Niagen At-Home Injection Kit (NR chloride 500 mg, ~28 days)
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Niagen Plus

+Backed by a public company with 25+ years of NAD+-precursor research; it holds the patent on the active ingredient (Niagen NRCl)
+Compounded by a 503B outsourcing facility (FDA-registered, cGMP) rather than a patient-specific 503A lab alone
+Flat, published $149 kit price includes the provider consult, a ~28-day supply, supplies and free Next Day Air shipping
−Only one product, and it is NR (an NAD+ precursor), not NAD+; the studies comparing it with NAD+ IV are small and company-sponsored
−The kit showed 'more stock coming soon' at the time of research, so availability is not reliable
−The site does not name the telehealth medical group or the dispensing 503A pharmacy
Read the full Niagen Plus review →

Renew Youth

+About 27 years in hormone therapy, one of the longest operating histories among brands reviewed
+Full-spectrum hormone care for both sexes, including thyroid, DHEA/pregnenolone, and adrenal support alongside testosterone and estrogen/progesterone
+4.6/5 Trustpilot rating across about 260 reviews, with the company replying to every negative review
−No pricing published anywhere on the site; costs are disclosed only after a phone consultation
−Treatment pages make overstated safety claims (e.g., testosterone "does not cause prostate cancer," therapy should have "no side effects")
−Reviewers report week-long prescription processing on top of shipping time
Read the full Renew Youth review →

Niagen Plus vs Renew Youth — FAQ

Is Niagen Plus better than Renew Youth?

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Niagen Plus scores higher overall in our independent evaluation (64.7/100 vs 61.2/100), leading on trust & safety, value. Renew Youth comes out ahead on experience, product range, reputation.

What do Niagen Plus and Renew Youth both offer?

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Both platforms treat Longevity & Peptides. Niagen Plus covers 1 treatment category total and Renew Youth covers 7.

Still deciding?

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