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Niagen Plus vs Tuyo Health: Which Is Better?

Head-to-head comparison of Niagen Plus and Tuyo Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Tuyo Health scores higher overall in our independent evaluation (67.2/100 vs 64.7/100), leading on value, experience, product range. Niagen Plus comes out ahead on trust & safety, reputation.

65

Prescription-only telehealth program from Nasdaq-listed Niagen Bioscience (formerly ChromaDex) selling an at-home injection kit of nicotinamide riboside (NR), an NAD+ precursor, rather than NAD+ itself.

Visit Niagen Plus
67

Tuyo Health is a Miami-based, physician-founded bilingual (Spanish/English) telehealth service offering GLP-1 weight loss, testosterone, ED, hair loss, birth control, and low-cost primary care to a primarily Latino patient base.

Visit Tuyo Health

Score Breakdown

DimensionNiagen PlusTuyo Health
Overall Score64.7/10067.2/100 ✓
Trust & Safety30%78/100 ✓56/100
Value25%70/10074/100 ✓
Experience20%58/10068/100 ✓
Product Range15%36/10082/100 ✓
Reputation10%68/100 ✓60/100

At a Glance

Founded20242024
HeadquartersLos Angeles, CAMiami, FL
Publicly tradedYes (NAGE)No
Treatment categories18
Treatments listed113
Starting price$149/mo$4/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryNiagen PlusTuyo Health
Longevity & Peptides$149
Niagen At-Home Injection Kit (NR chloride 500 mg, ~28 days)
$145
Sermorelin Injection

Niagen Plus

+Backed by a public company with 25+ years of NAD+-precursor research; it holds the patent on the active ingredient (Niagen NRCl)
+Compounded by a 503B outsourcing facility (FDA-registered, cGMP) rather than a patient-specific 503A lab alone
+Flat, published $149 kit price includes the provider consult, a ~28-day supply, supplies and free Next Day Air shipping
−Only one product, and it is NR (an NAD+ precursor), not NAD+; the studies comparing it with NAD+ IV are small and company-sponsored
−The kit showed 'more stock coming soon' at the time of research, so availability is not reliable
−The site does not name the telehealth medical group or the dispensing 503A pharmacy
Read the full Niagen Plus review →

Tuyo Health

+Fully bilingual (Spanish/English) care team, a meaningful access differentiator for Spanish-speaking patients
+Physician-founded, with a named medical director (Dr. Germán Echeverry, MD)
+Transparent, low published pricing: compounded semaglutide from $155/mo with labs every 3 months and no membership fee; finasteride $18/mo; primary care $9.99/mo
−Received an FDA warning letter (September 2025) for marketing compounded semaglutide and tirzepatide as the "same active" ingredient as Wegovy, Ozempic, Zepbound, and Mounjaro
−Operates in only 20 states
−Reviewers report slow refunds and a $129 initial fee charged to patients later found unsuitable for the program
Read the full Tuyo Health review →

Niagen Plus vs Tuyo Health — FAQ

Is Niagen Plus better than Tuyo Health?

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Tuyo Health scores higher overall in our independent evaluation (67.2/100 vs 64.7/100), leading on value, experience, product range. Niagen Plus comes out ahead on trust & safety, reputation.

Is Niagen Plus or Tuyo Health cheaper?

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Tuyo Health has the lower starting price (from $4/mo vs $149/mo for Niagen Plus). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Niagen Plus and Tuyo Health both offer?

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Both platforms treat Longevity & Peptides. Niagen Plus covers 1 treatment category total and Tuyo Health covers 8.

Still deciding?

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