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Synergy Rx vs Tuyo Health: Which Is Better?

Head-to-head comparison of Synergy Rx and Tuyo Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Tuyo Health scores higher overall in our independent evaluation (67.2/100 vs 51.9/100), leading on trust & safety, value, experience, product range, reputation.

52
Synergy Rx
Below Average

Synergy Rx is a GLP-1 and peptide storefront launched in 2026 on CareValidate's white-label platform. It sells compounded semaglutide and tirzepatide as injections or oral tablets, prescribed through the Lion MD network.

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67

Tuyo Health is a Miami-based, physician-founded bilingual (Spanish/English) telehealth service offering GLP-1 weight loss, testosterone, ED, hair loss, birth control, and low-cost primary care to a primarily Latino patient base.

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Score Breakdown

DimensionSynergy RxTuyo Health
Overall Score51.9/10067.2/100 ✓
Trust & Safety30%48/10056/100 ✓
Value25%60/10074/100 ✓
Experience20%50/10068/100 ✓
Product Range15%58/10082/100 ✓
Reputation10%38/10060/100 ✓

At a Glance

Founded20262024
Headquarters—Miami, FL
Publicly tradedNoNo
Treatment categories38
Treatments listed913
Starting price$109/mo$4/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategorySynergy RxTuyo Health
Weight Loss / GLP-1$199
Compounded Semaglutide (injectable)
$99
Metformin (weight program)
Longevity & Peptides$109
B12 Methylcobalamin
$145
Sermorelin Injection
Sexual Health$275
PT-141 (bremelanotide)
$4–$7
Generic Sildenafil / Tadalafil

Synergy Rx

+Offers both injectable and oral-tablet compounded semaglutide and tirzepatide
+Names its four dispensing pharmacies and supervising Lion MD physicians
+Wider peptide menu than sibling storefronts: NAD+, sermorelin, glutathione, B12, PT-141
−Independent review found the intake does not screen for medullary thyroid cancer or MEN2 history (GLP-1 boxed-warning contraindication)
−Pricing is withheld until after the consult on the brand's own site; consult fee is disclosed inconsistently ($59 vs $80)
−Launched in 2026 with no Trustpilot, BBB or patient-review history
Read the full Synergy Rx review →

Tuyo Health

+Fully bilingual (Spanish/English) care team, a meaningful access differentiator for Spanish-speaking patients
+Physician-founded, with a named medical director (Dr. Germán Echeverry, MD)
+Transparent, low published pricing: compounded semaglutide from $155/mo with labs every 3 months and no membership fee; finasteride $18/mo; primary care $9.99/mo
−Received an FDA warning letter (September 2025) for marketing compounded semaglutide and tirzepatide as the "same active" ingredient as Wegovy, Ozempic, Zepbound, and Mounjaro
−Operates in only 20 states
−Reviewers report slow refunds and a $129 initial fee charged to patients later found unsuitable for the program
Read the full Tuyo Health review →

Synergy Rx vs Tuyo Health — FAQ

Is Synergy Rx better than Tuyo Health?

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Tuyo Health scores higher overall in our independent evaluation (67.2/100 vs 51.9/100), leading on trust & safety, value, experience, product range, reputation.

Is Synergy Rx or Tuyo Health cheaper?

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Tuyo Health has the lower starting price (from $4/mo vs $109/mo for Synergy Rx). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Synergy Rx and Tuyo Health both offer?

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Both platforms treat Weight Loss / GLP-1, Longevity & Peptides, Sexual Health. Synergy Rx covers 3 treatment categories total and Tuyo Health covers 8.

Still deciding?

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