9 Best Tretinoin Providers of October 2026
Quick answer
As of October 2026, our top-rated place to get Tretinoin online is Twentyeight Health (7.5/10), followed by Hello Alpha (from $20/mo) and Miiskin (from $48.99/mo). Across the 9 providers we compared, starting prices run $20–$75/mo (median $33).
- Our #1 pick1Twentyeight Health
- Offers Prescription Skincare (acne, melasma, anti-aging); price not published before intake
- Price includes provider visits and shipping
- One membership covers contraception, EC, UTI/BV/yeast, herpes, skincare and weight care, and urgent-care…
7.5Very Good - 3Miiskin
- From $48.99/mo for Custom Acne/Anti-aging Formula (tretinoin-based)
- Pricing is published: $59–69 new consult, $39 renewal, custom formulas $48.99–68.99
- Patient can choose FDA-approved generics filled at any pharmacy instead of being steered to compounded…
7.1Good - 4CurologyNames Its Pharmacy
- From $30/mo for Custom Formula
- Offer: First 30-day box for $5.45 S&H (new subscribers only)
- Price includes provider visits and shipping
6.9Good - 5Pallas HealthSame Price at Every DoseNames Its Pharmacy
- From $75/mo for Compounded Prescription Skincare
- Price includes provider visits and shipping
- Broad catalog for a new entrant: compounded and branded GLP-1s, NAD+, sermorelin, glutathione, women's HRT…
6.7Good - 6Musely
- From $50/mo for Aging Repair Cream
- Price includes provider visits and shipping
- Broad and unusually varied catalog spanning pigmentation, anti-aging, hair loss, and menopause care
6.5Good - 7Evernow
- Offers Tretinoin Face Cream; price not published before intake
6.4Fair - 8Push Health
- Offers Acne Treatment; price not published before intake
5.6Fair - 9Dear Brightly
- From $33/mo for Night Shift
- Offer: $66 for first 2-month supply, then ~$99/quarter
- Price includes provider visits and shipping
5.5Fair
Side-by-side comparison
| # | Provider | Score | From | Intro offer | Labs |
|---|---|---|---|---|---|
| 1 | Twentyeight Health | 7.5 | See site | — | — |
| 2 | Hello Alpha | 7.4 | $20/mo | — | — |
| 3 | Miiskin | 7.1 | $48.99/mo | — | — |
| 4 | Curology | 6.9 | $30/mo | Yes | — |
| 5 | Pallas Health | 6.7 | $75/mo | — | — |
| 6 | Musely | 6.5 | $50/mo | — | — |
| 7 | Evernow | 6.4 | See site | — | — |
| 8 | Push Health | 5.6 | See site | — | — |
| 9 | Dear Brightly | 5.5 | $33/mo | Yes | — |
Starting prices as listed on each provider's site, checked Oct 9, 2026. Prices can change with dose, plan length and promotions.
Key numbers
- 9 providers compared
- Lowest starting price: $20/mo
- Median starting price: $33/mo
- 0 of 9 include lab work in at least one plan
- 2 of 9 have an intro offer or first-month discount
How we ranked these
Ranked by our category score: trust and safety (30%), value (25%), patient experience (20%), product range in this category (15%) and reputation (10%). Scores come from our own research into each provider's website, regulatory records, patient reviews and pricing. Read the full methodology
What to look for
What tretinoin is
Tretinoin is a prescription topical retinoid, a vitamin A derivative, applied to the skin as a cream or gel. It is FDA-approved for acne, and one low-strength emollient formulation is approved for fine wrinkles and sun damage. It is one of the best-studied ingredients in dermatology. Online skincare services prescribe it alone or mixed into custom compounded formulas with ingredients such as niacinamide, azelaic acid, or clindamycin.
How it works
Tretinoin binds retinoic acid receptors in skin cells, speeding cell turnover and normalizing how pores shed, which prevents the clogged follicles that become acne. With longer use it also stimulates collagen production and evens out pigmentation, which is why it improves fine lines and sun damage. Strengths run from about 0.01% to 0.1%; higher is stronger but more irritating.
What to expect
Expect an adjustment period of dryness, peeling, and sometimes a temporary acne flare ("purging") in the first 2–6 weeks. Acne usually improves noticeably by 8–12 weeks. Changes in fine lines and pigmentation take 3–6 months or longer.
Who it's not for
People who are pregnant or trying to conceive, unless their prescriber specifically approves it; People with eczema or broken, sunburned skin in the treatment area; Anyone unwilling to use daily sunscreen.
Frequently asked questions
Where is the best place to get Tretinoin online?
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Twentyeight Health ranks #1 on this list with a score of 7.5/10. Scores weigh trust and safety, value, patient experience, product range and reputation.
What is the cheapest way to get Tretinoin online?
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Of the providers on this list, Hello Alpha has the lowest starting price at $20/mo (Rx Acne / Skincare (Tretinoin)). Starting prices often rise with dose or after an intro period, so compare the ongoing price too.
How much does Tretinoin cost online?
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Across the 9 providers we compared, starting prices range from $20 to $75 per month, with a median of $33. 2 of them run an intro offer or first-month discount.
How are these providers ranked?
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By our category score: trust and safety (30%), value (25%), patient experience (20%), product range in this category (15%) and reputation (10%), with a small bonus for specialists. The full methodology is published on our methodology page.
Is tretinoin the same as retinol?
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No. Retinol is an over-the-counter ingredient that the skin has to convert into retinoic acid, so it is much weaker. Tretinoin is retinoic acid itself, which makes it more effective but also more irritating, and it requires a prescription.
Is tretinoin FDA-approved for wrinkles?
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One low-strength emollient formulation is FDA-approved to help with fine wrinkles and sun damage. Most other tretinoin products are approved for acne, and using them for anti-aging is off-label but very common. Custom compounded formulas from online skincare services are not FDA-approved products.
Can I get tretinoin online?
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Yes. Many telehealth dermatology services prescribe tretinoin after an online consultation, usually with photos of your skin. Some prescribe generic tretinoin from a regular pharmacy, and others ship their own compounded formulas.
How should I start tretinoin?
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Start with a low strength, a pea-sized amount for the whole face, two or three nights a week, and build up as your skin tolerates it. Use a moisturizer and daily sunscreen.